Katherine Heigl and T.R. Knight Leaving ‘Grey’s Anatomy’

Katherine Heigl and T.R. Knight’s Grey’s Anatomy co-star James Pickens Jr. has confirmed to Us Magazine that the two actors are leaving the ABC show.

When Pickens was asked if Heigl, 30, was doffing her scrubs, Pickens replied, “Yes, she is. Wherever Katherine goes, I wish her nothing but the best.”

And her best friend in real life reportedly won’t be too far behind her.

“He’s going too,” Pickens said of Knight at an NAACP Awards luncheon. “He just wanted to pursue other career paths.”

Knight, 35, has reportedly wanted out of his Grey’s contract for some time and is “not shy about telling people,” according to a source. And some feel sooner is better than later.

“He complains to Katherine all the time,” a source on the set said. “The energy on set will be much better when he’s gone.”

The two actors’ characters haven’t fared well this season.

Knight has little screen time, and Heigl’s character was written to be in a love affair with her ex. Who’s dead.

Then again, Katherine probably isn’t the writers’ favorite actress to write for.

Heigl and Knight’s reps aren’t commenting, and ABC has not made an official announcement as of yet.