Chelsea Handler Trashes Angelina Jolie AGAIN!

Chelsea Handler isn’t done raking Angelina Jolie over the coals just yet.

The Chelsea Lately host, who earlier this week made headlines with a videotape of a live performance in which she lambasted the Salt beauty as a “homewrecker” and a “f*cking c*nt,” once again takes a few digs at Jolie in a Glamour interview conducted by Katie Couric. In the interview, Handler opines,

“Yeah, I’m not a fan. She just doesn’t come off to me as a sincere woman. She seems like a woman that you’d really want to avoid.”

So what’s her big beef with Jolie? Well, it might have something to do with Handler’s declared fondness for Jennifer Aniston, who was famously married to Brad Pitt before he took up with Jolie. In the same interview, Handler sings the praises of the former Friends gal—with whom she recently vacationed in Mexico—gushing,

“Jennifer Aniston makes me laugh. She’s irreverent and hilarious, and she sends me really, really funny e-mails.”

Presumably, the only thing Jolie will be sending Handler anytime soon is daggers from her eyes if the two should cross paths.

Who do you side with in this fiery debate: Handler, or Jolie? Sound off in the comments section.