"The truth is we got to know each other because of a substantive issue. He is a terrific advocate on behalf of the people of Darfur, and to the people of Sudan who've been brutalized for a long time. And so when I was a senator, this was well before I was president, that was an issue that I was working together on a bipartisan basis, and George who had traveled there, done documentaries there, and was very well-informed, came to testify in Congress."
He added: "And so we got to know each other, and he is a good man, and a good friend."
But what does first lady Michelle Obama have to say about Clooney?
Like most Americans, the first lady calls the actor "cute." Unfortunately for her, she never seems to be around when Clooney visits the Oval Office. "It's a conspiracy … All the meetings, I just happen to be busy," Michelle joked to ET.
The president also weighed in on the joke. "Michelle is always frustrated because a lot of the events that George has been involved in, for some reason, she has something else going on."
But the first lady isn't the only one eager to meet the actor. "I will say that the couple of times he's come to the White House, I notice that the staff suddenly is circling around my office. They've got memos they need to make sure I see right away."