Anthony Edwards reprised the role of Dr. Mark Greene on last week’s episode, and Noah Wyle and Eriq La Salle are set to return.

Margulies, 42, played nurse Carol Hathaway on NBC’s ER beginning with the show’s fall 1994 premiere. She left after six seasons, in 2000. ER is ending now in its 15th season.

“I feel like I left Carol Hathaway in the best scenario possible,” Margulies told the AP. “I can’t imagine making it any better than that.”

Her character moved to Seattle to live with George Clooney‘s Dr. Doug Ross.

While anticipation is high, there’s still no official word that Clooney will return before the show is put to rest.

“From what I heard, George said, ‘Absolutely,’ schedule permitting,” Wyle says.

This would probably be news to Clooney, as it was previously reported that he had said “no” to the request to return.

Clooney’s last appearance on the show was a surprise to millions in 1998 when he secretly showed up for cast member Julianna Margulies‘ last episode.

ER is pulling out all the stops for the final season. Anthony Edwards is coming back despite his character having died, and so is Eriq LaSalle. No word on whether Marguiles or any other originals will be pushing gurneys.

On a related note, news came earlier this week that ER creator Michael Crichton passed away.