Nick and Joe Jonas Cover ‘Can’t Take My Eyes Off Of You’ With John Stamos: 5 Other Unlikely Musical Collaborations (VIDEOS)

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The Jonas Brothers are jamming with Uncle Jesse? No, this isn’t a dream, folks!

Former Disney stars Nick and Joe Jonas recently shared the stage with Full House actor John Stamos during the latter’s set at The Bitter End in New York City.

The unlikely trio surprised the audience with a sultry rendition of “Superstition” and “Can’t Take My Eyes Off Of You,” with Joe and Nick on vocals while Stamos rounded out percussion duty.

However, this actually wasn’t the weirdest musical collaboration in Hollywood history.

Read on as Celebuzz counts down the top 5 most outrageous duets, below.

5. Mariah Carey and Justin Bieber: It makes perfect sense that two pop sensations would join forces to create one supersong, but Carey and Bieber’s rendition of “All I Want For Christmas Is You” left critics with a bitter taste in their mouths. The reason: Everyone was shifting uncomfortably in their seats when the 41-year-old Carey pranced around in front of the 17-year-old Bieber in nothing but a skimpy Santa Claus costume for the music video.

4. David Bowie and Bing Crosby: David Bowie crashed crooner Bing Crosby’s 1977 TV special Bing Crosby’s Merrie Olde Christmas and the unlikely duo launched into a bizarre rendition of “The Little Drummer Boy” and “Peace on Earth.” According to Rolling Stone, Bowie didn’t want to do the song but Crosby put his foot down, forcing the British rocker to awkwardly sing along to the Christmas tune.

3. Eminem and Elton John: In 2001, Eminem was notorious for the abundance of anti-gay slurs in his songs. So when he hit the Grammys stage with Elton John — who is openly gay — many fans were shocked to see the total opposites collaborating so well on Slim Shady’s hit song, “Stan.”

2. Jessica Simpson and Ozzy Osbourne: One sung bubblegum pop during the early 2000’s, the other bit off a bat’s head like it was bubblegum. Needless to say, no one saw this duet coming.

1. Elmo and Andrea Bocelli: Defying genre and, um, species, Sesame Street’s Elmo and classical singer Andrea Bocelli tops the list with their rendition of “Time To Say Goodnight.”