Khloé Kardashian Hosts ‘Chelsea Lately,’ Jokes She F*cked O.J. Simpson Once

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The Game and Kim?
Rapper says he dated Khloe's sister.
Khloé Kardashian can take a joke, and deliver them pretty damn well, too.

The 29-year old Keeping Up With the Kardashians star took over hosting duties for late night’s Chelsea Handler last night and the statuesque brunette poked fun at the tabloid rumors about her famous family. Oh, and she also said she slept with O.J. Simpson, but “only once.”

Khloé, who just posted her first Vine video, was a natural onstage as she delivered the monologue for Chelsea Lately. Perhaps Kris isn’t the family member who should have been given the talk show.

Check out Khloé on last night’s show in the video above.